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ngq, you sexy beast! Here is a sanity check for that clean meta. ;)

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  • Soaring drug prices could bar access to future coronavirus treatments (Guardian)
    • COVID-19 exposes drug supply gaps as Canada explores local ‘Made in Canada’ solutions (CTV News)
  • To deliver a COVID-19 vaccine equitably, we must start planning now (Devex)
    • U.S. taxpayer funding contributed to research for a remdesivir patent that will likely remain inaccessible to many people due to the $4,500 price tag by Gilead (STAT)
  • Protect against market exclusivity in the fight against COVID-19 (Nature Medicine)
    • Compulsory Licensing: A Cure for Distributing the Cure? (CSIS)
  • Mobile apps that allow real-time tracking of self-reported symptoms are effective in predicting infections, according to a new study in Nature Medicine
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  • A new report by the World Bank projects the sharpest historic decline in global remittances could push 40-60 million people into extreme poverty
    • The UNHCR warns of the impact of reduced remittances on migrants and vulnerable communities, issuing a new guidance on Cash and Voucher Assistance programs
  • A UNDP report warns of the alarming increase of gender-based violence due to COVID-19
    • COVID-19 Pandemic Could Have Long-Term Consequences On Women’s Health Care Access Globally, Health Workers (UNFPA)
    • Care and Connection in Crisis: Feminist Strategy to Confront COVID-19 (Madre)
    • Commentary: We need a feminist response to the pandemic (Devex)
  • Like Zambia, more African countries seek emergency funding from the IMF
  • A ban on large funerals in South Africa has forced people to give up many traditions, but they have also rediscovered old ones, including “secret burials” (BBC)
  • By prioritizing Early detection, contact tracing and 28 day quarantines, Kerala’a COVID-19 fatality rate (0.53%) is the lowest in India, and has limited the spread of the virus without inflicting any of the human suffering seen in other parts of the country (Commentary: The Kerala Model (Shashi Tharoor)
  • In a new commentary, Tony Blair and Agnes Kalibata highlight four global actions to increase food security during the pandemic. These including: (1) Increasing funding for food-relief and social-protection measures; (2) Investing in local agricultural production; (3) Supporting regional and local logistics hubs to limit disruptions to food and agricultural produce supply chains; and (4) Incentivizing funding of agro-processing and Agtech companies.
    • DIGHR Fellow Rhonda Ferguson also argues that displacement of local food systems threaten 265 million people with famine, and that transformation in trade is urgently needed (Conversation)
    • HIV and Food Insecurity: A Syndemic Amid COVID-19 (AIDS and Behaviour)
    • Small-scale farmers can help build resilient food systems in post-COVID world (IFAD)
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  • A new WHO study projects that up to 190,000 people in Africa could die and an additional 29-44 million could get infected by the Coronavirus in the first year if containment measures fail.
  • Harvard Professor Joseph Nye – one of the world’s leading scholars on global governance- examines the “abysmal failure of leadership” from the U.S. and China, urging that more global solidarity and recognition of mutual interest is essential to address the pandemic
  • In collaboration with DIGHR, the Ilisaqsivik Society, and Médecins Sans Frontières (Latin), SeeChange Initiative is launching a Community Roadmap planning tool today to support communities organize, prepare and respond to COVID-19. See:
    • CommunityFirst COVID-19 Emergency Readiness Checklist
    • What the Covid-19 pandemic is teaching us about community (STAT)
  • In a commentary, Nobel Peace Prize laureate, Kailash Satyarthi, highlights the compassionate work of community and civil-society groups working with vulnerable populations, urging G20 to increase international aid and coordination through UN agencies like WHO, UNICEF and UNOCHA.
  • A study in Lancet Global Health projects an additional 0.25-1.2 million children under 5 could die indirectly in the next six months as a result of the pandemic though disruption of health systems and decreased access to food. This would be the first increase in global child mortality since World War II. The researchers from Johns Hopkins also estimate that indirect maternal deaths could rise from 8% to 38%.
  • An analysis by the New York Times reveals spikes in fatalities across Latin America (including Brazil, Ecuador and Peru) that exceed the worst pandemic trajectories in Europe and the U.S. The Brazilian president, when asked about the death toll, replied “So what? What do you want me to do?”.
  • Amazon indigenous leaders warn of the potentially devastating effects of COVID-19 (New Humanitarian), where “no specific attention has been given to indigenous communities”.In Brazil, the potential effects highlight the lack of government support with food and health services. The former health minister of Ecuador, meanwhile, warns that “everyone is at risk” if marginalized communities are not able to afford basic health services, while officials in Mexico suggest that thousands of deaths are not being reported, obscuring the true toll of the COVID-19 epidemic.
  • China, South Korea and Japan are experiencing a resurgence in COVID cases, as the WHO and public health experts warn against lifting containment measures too early (CNBC)
    • Authorities in Wuhan plan to test all 11 million residents over the next ten days after discovering new infections for the first time since its lockdown was lifted, prioritizing vulnerable groups and high-density areas (BBC)
  • Exceptionally heavy seasonal rains across East Africa since late April have resulted in widespread floods that caused a heavy loss of life and property, compounding the risks to human health and food security from the COVID-19 pandemic and the most serious desert locust invasion in decades. (WMO)
  • COVID­19 epitomises why a “One Health” approach – which recognises the fundamental interconnectedness of humans, animals, and their shared environment-  is key to ensuring the healthy and sustainable future of the planet. co­Chairs of the Lancet One Health Commission are  calling for a COVID-19 One Health Research Coalition (Lancet)
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  • Two papers suggest that the Infection Fatality Rate (IFR) for COVID-19 may be “significantly higher” than previously thought. In Health Affairs, authors estimates an IFR of 1.3% among symptomatic cases in the U.S., while a paper in the Journal of Econometrics cautions against comparison due to variability across countries in testing strategies and testing accuracies.
  • WHO Europe issued a new guidance document that recommends expanding nurse-led models of care to improve access to care to during the pandemic
  • In collaboration with the WHO, the U.S. CDC is launching a new weekly webinar series for Infection Prevention & Control in healthcare settings. The first webinar on ‘Triage of COVID-19 Patients: Operational Considerations and Practical Examples’ will be Thursday, May 14
    • Johns Hopkins offers a free online course on Contact Tracing (Coursera)
  • A paper in the Journal of Virology and a commentary in GUT point to gastrointestinal symptoms like diarrhoea, nausea and vomiting in a quarter of patients in China
  • A new study suggests that patients with mild cases cleared the Coronavirus in five less days on a combination of interferon beta-1b, lopinavir-ritonavir and ribavirin (Lancet)
  • Patients that have recovered from COVID-19 are selling their blood plasma at significant prices to healthy patients that believe it will confer immunity (KHN, WSJ)
[post_title] => Snapshot of Clinical Public Health [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => snapshot-of-clinical-public-health-2 [to_ping] => [pinged] => [post_modified] => 2020-08-13 22:32:59 [post_modified_gmt] => 2020-08-14 02:32:59 [post_content_filtered] => [post_parent] => 0 [guid] => https://covid19.dighr.org/developments/snapshot-of-clinical-public-health-2/ [menu_order] => 0 [post_type] => development [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 2401 [post_author] => 1 [post_date] => 2020-05-10 16:15:22 [post_date_gmt] => 2020-05-10 20:15:22 [post_content] =>

Making waves: Coronavirus detection, presence and persistence in the water environment: State of the art and knowledge needs for public health (Water Research)

Linking aerosol characteristics of size distributions, core potential pathogens and toxic metals to wastewater treatment process (Environmental Pollution)

The Global WASH Cluster issues a Guidance document on mitigating the socio-economic impacts of COVID-10 on the Water, Sanitation and Hygiene Sector

Water security beyond COVID-19 (Governance and Social Development Resource Centre)

Refugee shelters in Mexico need access to soap and hygiene products, according to UNHCR

UNICEF issues Guidance on WASH and Infection Prevention and Control in health care facilities

Floods in Burundi cause destruction amid pandemic (UNOCHA)

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World leaders pledge $8 billion for research into vaccine and therapies as well as equitable and timely distribution (Coronavirus Global Response Summit)

The absence of the U.S., India and Russia points to possible fractures in global health diplomacy (Washington Post)

Vaccine could be available as early as 9-24 months (Gates Foundation)

A vaccine likely won’t be available until the end of 2021 due to Phase 2 and 3 clinical trials to ensure safety and efficacy, according to the chair of the WHO Global Outbreak Alert and Response Network (CNBC)

Nature: Multiple vaccines are in competition: how will scientists choose the best?

Rapid review for the anti-coronavirus effect of remdesivir (Drug Discoveries & Therapeutics)

Video: How does Gilead’s drug remdesivir work against coronavirus? (STAT)

Gilead to charge up to US$4,500 for experimental COVID-19 treatment remdesivir (Institute for Clinical and Economic Research)

WHO to engage U.S. and Gilead as data on safety and efficacy emerge to ensure wider availability of remdesivir (CNBC)

GAVI Vaccine Alliance proposes an Advanced Market Commitment program for COVID-19 vaccine (GAVI)

Internet of Things has been deployed in innovative ways to provide information and monitoring during the COVID-19 epidemic, including automated and transparent treatment (Journal of Diabetes & Metabolic Syndrome)

Emerging technologies to combat COVID-19 pandemic (J of Clinical and Experimental Hepatology)

Going Viral: how to boost the spread of coronavirus science on social media (Nature)

COVID-19 has reinforced the importance of preprints as a means for rapid research dissemination (Nature Biotechnology)

Tool: Google releases an AI-powered COVID-19 Research Explorer to assist researchers with complex queries

 

UK researchers create antibody test claiming 100% sensitivity, 99.8% specificity and results in 35 minutes (UK Standard)

U.S. Food and Drug Administration tighten standards for antibody testing following false specificity and sensitivity claims (WSJ)

Ethical and practical challenges of COVID-19 human vaccine trials (STAT)

Human Challenge Studies to Accelerate Coronavirus Vaccine Licensure (Journal of Infections Diseases)

WHO to issue ethical guidelines this month to inform human challenge trials amidst reports of deliberate infection of healthy human volunteers to test vaccine candidates (SCMP)

Frontier technologies for COVID-19 need better governance (WEF)

Unproven herbal remedy, ‘Madagascar Tonic’, touted by some African governments despite warnings from health officials (Globe & Mail; The Economist)

 

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UNOCHA updated the COVID-19 Global Humanitarian Response Plan, appealing for US$6.7 billion for immediate support for pandemic response in fragile countries

COVID-19 has “unleashed a tsunami of hate and xenophobia, scapegoating and scare-mongering” around the world, according to the UN Secretary-General (Guardian)

Institute of Migration issue Communication Guidance in response to the rise of anti-migrant sentiment in the face of the COVID-19 pandemic

Local response in health emergencies: key considerations for addressing the COVID-19 pandemic in informal urban settlements (Environment and Urbanization)

A new report by Rescue International shows how restrictions on mobility, lack of information, increased isolation and fear have led to a decrease in women being able to report incidents of domestic violence.

COVID-19 on the African continent (The Lancet Infectious Diseases)

IOM Chief of Mission in the DRC reports how the experiences and capacity developed to fighting Ebola have informed the COVID-19 response

Schools remain locked for more than 127 million children in S.E. Africa (UNICEF)

There are reports that some African governments are promoting an unproven herbal remedy called ‘Madagascar Tonic’ despite warnings from health officials (Globe & Mail)

Health system quality in the time of COVID-19 (The Lancet Global Health)

Food insecurity in West Africa could leave 43 million at risk as coronavirus hits (UN News)

UNOCHA issues global attention to food insecurity in humanitarian response locations

A new report by the UNDP reveals major disparities among countries in their ability to respond and recover from the pandemic (COVID-19 and Human Development: Exploring Global Preparedness and Vulnerability)

Collateral damage of lockdown in India (BMJ)

Local response in health emergencies: key considerations for addressing the COVID-19 pandemic in informal urban settlements (Environment and Urbanization)

Slums are the next front line in the fight against the coronavirus (Devex)

Mental health and COVID-19: change the conversation (The Lancet)

UNOCHA releases Rapid Learning Review that outlines 14 actions, insights and concepts for humanitarian actors in their COVID-19 responses (ALNAP)

The threat of COVID-19 in Syrian war refugee camps (Travel Medicine & Infectious Disease)

Emerging challenges of securing mental well-being in conflict settings (Asian Journal of Psychiatry)

UNOCHA issues global attention to food insecurity in humanitarian response locations

Human rights approach to Emergency Response? Advocacy of Canada’s Human Rights Commissions During the COVID-19 Crisis (Canadian Journal of Political Science)

Institute of Migration issue Communication Guidance in response to the rise of anti-migrant sentiment in the face of the COVID-19 pandemic

Prisons have become ‘petri dishes,’ as inmates are unable to guard against virus (KHN)

Coronavirus abuse fears for women in South Sudan (New Humanitarian)

UN Women issues a Guidance Document on promoting gender-responsive participation in humanitarian settings (UN Women)

In Haiti, women’s organizations are at the heart of the response to COVID-19 (CECI)

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The Journal for Clinical Medicine Research published a systemic review that provides a comprehensive clinical summary of available data as well as preventive measures (Modern Pandemic: A Systematic Review from Front-Line Health Care Providers’ Perspective)

An article in JAMA (Choices for the ‘New Normal’) outline six lessons for clinical care. These include the changing pace of learning, the value of updated clinical guidelines, protecting the workforce, enabling virtual care, increasing preparedness for novel threats, and addressing issues of inequity.

Virus Mutations Reveal How COVID-19 Really Spread (Scientific American)

A new study by the U.S. Los Alamos National Laboratory found that a mutated strain of Coronavirus strain detected in Europe three months ago may be spreading faster than earlier versions, urging vaccine and drug developers to consider this new strain in produce solutions (Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2)

A new paper in the Journal for Clinical Medicine (Estimation of Unreported Coronavirus Infections from Reported Deaths) estimates that almost 92% total daily new infections were unreported based on the early outbreak of COVID-19 in China.

In the International Journal of Public Health, authors suggest three additional ways that the COVID-19 pandemic will affect health outcomes: increase in mortality due to the diversion of health resources, impact of the ensuing recession on health systems, and the consequence of potential austerity measures

Undiagnosed and untreated TB cases is expected to cause 1.4 million deaths, as global focus is on COVID-19 according to the Stop TB Partnership (Guardian)

Widespread population serological testing can be important in determining immunity (‘sero-protection’) as well as mitigation strategies among vulnerable populations (‘social sero-epidemiology’). At present, most tests have been limited in scope, as the quality of serologic tests also remains a challenge (Washington Post)

Immunity passports and vaccine certificates: scientific, equitable & legal challenges (Lancet)

WHO claims that prior reports of COVID-19 ‘reinfections’ were false positives (Guardian)

 

COVID-19 Riddle: why does the virus affect some countries and regions more than others? (NYT)

WHO urges public health basics and community surveillance strategies (WEF)

‘Risk-based’ social distancing key to reopening (WSJ)

Mass screening may have helped South Africa stem coronavirus tide (Financial Times)

 

[post_title] => Snapshot of Clinical Public Health [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => snapshot-of-clinical-public-health [to_ping] => [pinged] => [post_modified] => 2020-08-13 22:35:42 [post_modified_gmt] => 2020-08-14 02:35:42 [post_content_filtered] => [post_parent] => 0 [guid] => https://covid19.dighr.org/developments/snapshot-of-clinical-public-health/ [menu_order] => 0 [post_type] => development [post_mime_type] => [comment_count] => 0 [filter] => raw ) [8] => WP_Post Object ( [ID] => 2397 [post_author] => 1 [post_date] => 2020-05-10 16:11:22 [post_date_gmt] => 2020-05-10 20:11:22 [post_content] =>

An article in The Lancet (Has COVID-19 subverted global health?) emphasize the importance of context and equity as key principles of global health. In light of limited financial aid from wealthier countries, the authors urge developing countries to adopt policies that reflect their local context that focus on what is possible, acceptable, just, and sustainable.

What accounts was South Korea’s COVID Secret? Fast Testing, High-Tech Tracing, Zero-Tolerance Isolation (Atlantic)

Lockdown Is a Blunt Tool, We Have a Sharper One: Contact Tracing (NYT)

WHO issues a Technical Guidance on Contact Tracing for COVID-19 in Africa (WHO)

The U.S. can expect a series of ‘mini-epidemics’, as the flattening curve is misleading, as the CIDRP outlines three potential futures: recurring small outbreaks, monster wave, persistent crisis (NYT)

Where the latest models think we are headed and why they disagree (FiveThirtyEight)

Reopening some states can heighten risk of or recurring second waves in others (STAT)

Simulation: Ending restrictions earlier is associated with higher projected cases and deaths, but also quicker economic recovery according to a RAND Corporation online tool

In the New England Journal of Medicine, the authors provide two lessons in the Italian response to the pandemic, highlighting the important of testing of health care workers, and how “urgent and decisive” lockdown of the region earlier could have contain the epidemic (Adaptations and Lessons in the Province of Bergamio)

National Geographic reviews the lessons learned from national responses to the COVID-19 pandemic, including the spread of social mitigation, the effectiveness of travel restrictions, testing and the impact of speed of response on outbreak trajectory (How to measure your nation’s response to coronavirus).

It took the U.S. only seven days to exceed projected COVID-19 deaths for August (Newsweek)

A new paper in the Journal of Risk Research (Resilience in the face of uncertainty) describe how political interference undermined the ability of the U.K. National Health Service with COVID-19 preparedness and response. Similar to the Bank of England, the authors argue that national emergency preparedness requires greater independence.

While the full impact of the pandemic on food security remains unknown, Dr. Rhonda Ferguson (DIGHR Research Fellow) argues that the displacement of localized food systems require transformation in trade to protect the estimated 265 million people threatened by famine (Coronavirus: Another chance to transform the global food trade)

COVID-19 and Globalization (One Health)

Could COVID-19 mark a ‘turning point’ in the climate crisis? (WEF)

Effective transmission across the globe: the role of climate in COVID-19 mitigation strategies (Lancet Planetary Health)

Iran’s locust threats grow amid coronavirus pandemic, sanctions (New Humanitarian)

As the number of cases in Iran top 100,000, the spokesperson for the Health Ministry expressed concern in the “rising trend” over the least three days (Daily Star Lebanon)

Public Health Emergency of International Concern (PHEIC) Declaration for COVID-19 extended (WHO)

Why we can’t compare country responses to COVID-19: death rates, data and geography (WEF)

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Arguing that “as long as anyone is at risk from this virus, the entire world is at risk” and the urgent need to “accelerate the strengthening of sustainable health systems”, the WHO launched a new initiative this past week to accelerate the innovative development, production and equitable access to new COVID-19 diagnostics, therapeutics, and vaccines. The Access to COVID-19 Tools Accelerator aims to strengthen global collaboration across governments, civil society, academia, and the private sector. Citing the lack of equitable access to early HIV/AIDS treatment and to vaccine deployments during the 2009 H1N1 outbreak, the WHO Director General warned “we cannot allow that to happen again.”

This WHO Accelerator initiative would augment the WHO COVID-19 R&D Blueprint adopted in February, while the Drugs for Neglected Diseases Initiative earlier this month announced a parallel effort focusing on resource-poor settings. The COVID-19 Clinical Research Coalition includes over 70 institutions from over 30 countries and aims to accelerate research and access to priority needs of vulnerable populations. See: STAT COVID-19 Drugs and Vaccines Tracker.

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The doubling rate of confirmed COVID-19 cases dropped to once every 21 days from a high of once every 7 days on April 1. As some countries experience stabilizing or declining national death tolls, it has prompted attempts to loosen lockdown measures. This includes France, Italy and Spain, three of the world’s hardest hit countries (accounting for 20% of cases and a third of all COVID-related deaths worldwide). Germany is begun to relax lockdown measures, as face masks have become mandatory in public. The National Health Service of the United Kingdom set out a six-week plan to ‘return to normal’ following projections that the U.K. has ‘likely survived the first wave’ of the pandemic and will get close to testing targets. Despite a record daily increase in confirmed cases,South Africa restarted some mining operations, as India has also begun to ease lockdown measures following a drop in reported

As some Asian-Pacific countries such as Singapore experience major outbreaks in the second wave of transmission, hospitals across Europe have raised concerns. The WHO noted that many states also do not have adequate testing capacity needed to support a safe reopening strategy that can detect, trace and isolate new COVID transmission. China has meanwhile provided a guide on how countries can prevent a second wave, including compulsory masks in public, fines for failure to exercise public hygiene practices, as well as public markings for social distancing lanes.

The LSHTM is gathering data on hundreds of intervention measures from around the world to determine factors contributing to disease outbreak as well as relative effectiveness of control strategies. For example, to date, Hong Kong’s swift surveillance, quarantine and social-distancing measures – such as the use of face masks and school closures – helped to cut Coronavirus transmission with only 4 deaths in a (urban) population of 7.5 million. The LSHTM platform is being developed to support the WHO’s technical support to member states, and includes more than 1,100 volunteers, multiple universities, public health organizations and non-profits, including ACAPS which analyses humanitarian crises.

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Deaths that are definitively ascribed to COVID-19 are typically in severely ill people who have tested positive for the virus in a hospital. Studies now suggest that many more COVID-19 related mortalities may not be accounted for if these occurred among people were not tested or who died at home or in a nursing home. Estimates vary on the disparity between official reported mortality and what experts believe may be the true mortality rate. One study from Italy suggests that the number of deaths were two times higher than reported) – more than double the reported figure. The head of the public health authority in Germany yesterday also reported an increase in excess mortality.

A 14-country analysis that was commissioned by the Financial Times estimates that the death toll from COVID-19 could be 60% higher than official reports when comparing overall fatalities with baseline mortality in the previous five years. Another study by a team from Yale analyzed how many mortalities would have been expected in the first five weeks in the U.S. without the pandemic, concluding that the official figures were likely off by a factor of two. The researchers also warn of widespread reports of people with serious illnesses avoiding hospitals, which could furthermore under-estimate the true impact of COVID-19 on health systems globally.

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  • Soaring drug prices could bar access to future coronavirus treatments (Guardian)
    • COVID-19 exposes drug supply gaps as Canada explores local ‘Made in Canada’ solutions (CTV News)
  • To deliver a COVID-19 vaccine equitably, we must start planning now (Devex)
    • U.S. taxpayer funding contributed to research for a remdesivir patent that will likely remain inaccessible to many people due to the $4,500 price tag by Gilead (STAT)
  • Protect against market exclusivity in the fight against COVID-19 (Nature Medicine)
    • Compulsory Licensing: A Cure for Distributing the Cure? (CSIS)
  • Mobile apps that allow real-time tracking of self-reported symptoms are effective in predicting infections, according to a new study in Nature Medicine
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